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Prepare Your Fuzeon


Updated December 28, 2003

The new drug Fuzeon is not like other HIV medications. It must be mixed before it can be injected. Here is a step-by-step guide to properly mixing your Fuzeon. Fuzeon is a powder that must be mixed with sterile water before it can be injected. The process could take about 45 minutes so plan ahead.
Difficulty: Average
Time Required: 20-45 minutes

Here's How:

  1. Gather Supplies
    You will need (1)vial of Fuzeon powder at room temperature, (1)vial of sterile water provided with Fuzeon , (1)3cc syringe with a one inch needle (large syringe), (1) 1cc syringe with 1/2 inch needle (small syringe), alcohol pads and a sharps container.

  2. Prepare your supplies.
    First remove the syringes from their sterile packages and remove lids from Fuzeon vial and sterile water vial. Discard syringe wrappers and vial caps in the trash. Next wash hands with soap and water and clean the rubber tops of each vial with a alcohol pad (See tips 1 and 2 below).

  3. Drawing up the sterile water.
    First gently tap the Fuzeon vial to loosen the powder. Take the large syringe and pull back on the plunger, drawing 1.1cc of air into the syringe. Inject the 1.1cc of air into the vial. With the needle still in the vial, turn the sterile water vial upside down. Slowly pull back the syringe and withdraw 1.1cc of sterile water making sure there is no air in the syringe (See tip 3 below). Finally, remove the needle and syringe from the sterile water vial.

  4. Inject the sterile water into the Fuzeon Powder
    First insert the syringe with the sterile water into the Fuzeon vial at an angle. Slowly push the plunger of the syringe in, allowing the sterile water to drip down the sides of the Fuzeon vial and into the powder. After all the sterile water in the syringe is transferred to the Fuzeon vial, remove the needle and syringe and discard in the sharps container. (See tip 4 below)

  5. Gently mix the Fuzeon
    Gently roll the Fuzeon vial between your hands to help the powder mix with the sterile water and begin to dissolve.

  6. Allow the Fuzeon powder in the sterile water.Make sure no powder is stuck to the walls of the vial. Never shake the vial. Shaking will lengthen the dissolving process. Once dissolving starts, set the vial aside and allow to dissolve completely. This could take up to 45 minutes. Never use Fuzeon that doesn't dissolve completely or has undissolved particles. Once dissolved, Fuzeon must be used immediately or store in the refrigerator in the vial (See tip 5 below).

  7. Inject the Fuzeon
    Follow this link for step-by-step instructions on how to inject Fuzeon once it has be properly prepared.


  1. Once your hands are clean touch nothing but your supplies and the area around the injection site.
  2. If you touch the rubber stopper after cleaning it, wipe again with an alcohol pad.
  3. After withdrawing the sterile water, tap the syringe gently to remove any air bubbles that may have gotten into the syringe.
  4. Never reuse syringes.
  5. Never store Fuzeon in a syringe.

What You Need

  • (1) vial of Fuzeon at room temperature
  • (1) vial of sterile water provided with Fuzeon
  • (1) vial of sterile water provided with Fuzeon
  • (1) 1cc syringe with 1/2 inch needle (small syringe)
  • Alcohol pads and a sharps container
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