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Fuzeon (T-20, enfuvirtide)

A Unique Way to Treat HIV


Updated November 29, 2008

Subcutaneous injection

Usual Dosage
90mg (1cc) subcutaneous injection twice per day

Fuzeon is given by subcutaneous injection in the upper arm, abdomen or anterior thigh. Each injection should be given in a different site than the previous injection and not in a site that has a healing site reaction.

Side effects to report to your doctor:

  • Injection site reaction (itching, swelling, redness, pain, tenderness, hardened skin, bumps)

  • Bacterial pneumonia

  • Hypersensitivity reaction
    • Difficulty breathing
    • Fever
    • Nausea / vomiting
    • Rash
    • Blood in urine
    • Feet swelling

  • Sleep problems

  • Pain / numbness / tingling in feet and hands

  • Decreased appetite

  • Depression

  • Muscle pain

  • Pancreatitis


  • Once mixed, Fuzeon must be used immediately or stored in its vial in the refrigerator.

  • Never use Fuzeon that doesn't dissolve completely or has undissolved particles after mixing.

For more information on Fuzeon try About.com's Drug Finder.

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