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Needleless Injection System Shows Promise
Looking for An Easier Way to Administer Fuzeon

By Mark Cichocki, R.N., About.com

Updated: October 04, 2007

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

~Biojector 2000 update at the end of this article~

Recent data from a study in Brazil has shown that a needleless injection system can make Fuzeon (enfuvirtide) administration easier and more comfortable. The gas powered injection system called the Biojector 2000 produced drug availability similar to conventional subcutaneous injections that use a needle and syringe. In addition, the study illustrated many benefits of a needleless system over the conventional injection method. They include:

  • fewer injection site reactions
  • eases the fears of "needlephobic" patients
  • increased comfort
  • ease of administration
  • less risk of needlestick injuries
  • ease of disposal
  • improved adherence and acceptance of Fuzeon

How to Mix & Prepare Fuzeon

While the Biojector 2000 is not readily available at this time, its manufacturer, Bioject, has filed for FDA approval for its use with Fuzeon. It is not yet known whether the FDA will issue an approval.

Important Update!
As of October 2007, the makers of Fuzeon, Roche and Trimeris, have decided not to pursue their plan to market their drug Fuzeon with the Biojector 2000. They site severe side effects from the Biojector 2000 as the cause. Read more about their decision.

Sources:

  • Coletta, C.; "Trimeris Gives Up on Device to Inject HIV Drug"; Triangle Business Journal; 3 Oct 2007.

  • Susman, Ed; IAS: Needle-Less Injection System Makes Fuzeon Patient-Friendly ; Medpage Today; July 28, 2005.
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