CMV, or cytomegalovirus (si-to-MEG-a-lo-vi-rus), is a virus that is found in all parts of the world. For someone with HIV or AIDS, CMV can cause retinitis (blurred vision and blindness), painful swallowing, diarrhea, and pain, weakness, and numbness in the legs.
How is CMV spread?
CMV spreads from one person to another in saliva, semen, vaginal secretions, blood, urine, and breast milk. You can get CMV when you touch these fluids with your hands, then touch your nose or mouth. People can also get CMV through sexual contact, breastfeeding, blood transfusions, and organ transplants.
How can I protect myself from CMV?
You may already have CMV. However, you can take steps to avoid CMV, such as:
- washing your hands frequently and thoroughly
- using condoms
- talking to your doctor if you expect to receive a blood transfusion. Most blood banks dont screen blood for CMV.
If you work in a day care center, you should take these special precautions:
- wash your hands thoroughly after contact with urine or saliva
- avoid oral contact with saliva or objects covered with saliva (such as cups, pacifiers, toys, etc.)
- talk with your doctor about whether you should continue to work in a day care center.
How do I know if I have CMV?
A blood test can tell you if you have CMV, but this test is not commonly performed. CMV doesnt always cause symptoms. Some people have fatigue, swollen glands, fever, and sore throat when they first get CMV. But these are also symptoms of other illnesses, so most people dont know it when they get CMV.
How is CMV different for someone with HIV?
Once CMV enters a persons body, it stays there. Most people with CMV never get CMV-related diseases. However, in people with HIV or AIDS, the virus can cause severe disease.
How can I prevent CMV disease?
The most important thing you can do is to get the best care you can for your HIV infection. Take your antiretroviral medicine just the way your doctor tells you to. If you get sick from your medicine, call your doctor for advice. CMV disease mostly affects HIV-infected people whose CD4 cell counts are below 100. Oral gancyclovir (gan-CY-clo- veer) may be used to prevent CMV disease, but it is expensive, has side effects, and may not work for all people.
Adapted from brochures provided by the Centers for Disease Control, 2000.

