Question: What is a treatment failure?
Answer: Eventually, regardless of how well you adhere to your therapy, combinations of HIV medicines will become less effective. When your combination therapy no longer prevents HIV replication, the therapy is said to have failed. There are many causes of therapy failure. Most often your virus has changed (mutated) and has become less sensitive to your therapy. It is not unusual for a person to change combinations from time to time in order to keep HIV from multiplying.
