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Paxil (paroxetine) & Paxil CR (controlled release paroxetine)

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Updated November 30, 2008

Class:

Form:

  • Paxil: 10mg (yellow), 20mg (pink), 30mg (blue) and 40mg (green) tablets
  • Paxil CR: 12.5mg (yellow), 25mg (pink) and 37.5mg (blue) tablets

Dosage:

  • Paxil: the typical initial dose is 20mg/day but can be increased if needed up to 50mg/day
  • Paxil CR: PAXIL CR should be administered as a single daily dose, usually in the morning. Patients should be started on 12.5 mg/day. Dose changes should occur in 12.5-mg/day increments and at intervals of at least 1 week. The maximum dosage should not exceed 75 mg/day.

Instructions:

  • Paxil & Paxil CR (paroxetine) should be administered once daily in the morning
  • may be taken with or without food
  • the tablet should be swallowed rather than chewed.

Side effects to report to your doctor:

  • sexual dysfunction (ejaculatory delay)
  • insomnia or somnolence (drowsiness)
  • nausea / vomiting /diarrhea
  • dry mouth
  • dizziness
  • tremor

Precautions & Drug Interactions:

  • In order to minimize the opportunity for overdosage, prescriptions for paroxetine should be written for the smallest quantity of drug consistent with good patient management.
  • Don't take with MAOIs, thioridazine or pimozide.
  • Never stop taking Paxil or Paxil CR abruptly. Doing so may result in serious side effects.
  • Antidepressants can increase the risk of suicidal thinking in children and adolescents with Major Depressive Disorder (MDD) and other psychiatric disorders.

For More Information:

For more information on Paxil and Paxil CR try About.com's Drug Finder.

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