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Videx / Videx EC (didanosine)

From , former About.com Guide

Updated February 05, 2010

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Videx / Videx EC (didanosine)

Videx EC 400mg Capsule

Photo © Gold Standard

Classification:

Nucleoside Reverse Transcriptase Inhibitor (NRTI)

Form:

Videx
  • 25mg, 50mg, 100mg, 150mg, and 200mg white buffered tablets
  • 100mg, 167mg, and 250mg packets of buffered powder for reconstitution
  • 2G and 4G bottles of pediatric powder

Videx EC (enteric coated) capsules

  • 125mg (tan imporint)
  • 200mg (green imprint)
  • 250mg (blue imprint)
  • 400mg (red imprint)

Barr laboratories now sells a generic version of Videx EC called didansoine.

Since the advent of the Videx EC formulation, Videx buffered tablets are rarely used in adults.

Dosage:

One 400mg capsule once daily.

In regimens that contain Viread, the dose of Videx is lowered to one 250mg capsule once daily.

Instructions:

Enteric capsules
  • Take on an empty stomach 1 hour before or 2 hours after meals.
  • Take 1 hour before or two hours after taking Viread.
  • Capsules must be swallowed whole.
  • Never open capsules and sprinkle the contents on food or in liquid.

Wafers / tablets / powder

  • When taking the wafers, never swallow whole. The wafers must be chewed or dissolved in a liquid.
  • Dissolve the powder form in liquid to take.

Side Effects To Report To Your Doctor:

  • Fatal and non-fatal pancreatitis (inflammation of the pancreas) has occurred. Symptoms include abdominal pain, nausea, and vomiting.
  • Dry mouth or altered taste
  • Nausea / vomiting / diarrhea
  • Numbness, tingling, or burning sensation in feet, hands, or fingers

Drug Interactions or Incompatibility:

  • Pentamidine may increase the risk of pancreatitis.
  • Videx EC has been associated with lactic acidosis whose symptoms include flu-like illness, muscle aches, weakness, fatigue.

Speacial Warning!
Videx and Videx EC have been linked with cases of non-cirrhotic portal hypertension, a potentially serious disease of the liver. Speak with your doctor about your risk of portal hypertension before taking Videx or Videx EC.

For More Information:

To learn more about Videx EC, try About.com's Drug Finder.

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