1. Health
You can opt-out at any time. Please refer to our privacy policy for contact information.

Discuss in my forum

The Wholesale Price of HIV Drugs

Suggested Wholesale Price of Antiretroviral Drugs (Updated September 9, 2013)

By

Updated May 20, 2014

Used under a Creatives Commons license at https://www.flickr.com/photos/59937401@N07/6127242068/
Photograph © Images of Money

The wholesale price of HIV drugs is determined by a number of factors. Firstly, an independent Wholesale Acquisition Cost (WAC) is released by the manufacturer, which is essentially the asking price of a drug before any discounts or rebates are added for volume purchases and/or prompt payment.

From this, a Suggested Wholesale Price (SWP) is set. This is the price recommended by the manufacturer to wholesalers when determining prices for their customers (i.e. retailers, hospitals, institutions). The SWP is not the actual transaction cost, but rather a baseline from which wholesalers can make competitive pricing decisions.

By contrast, the Average Wholesale Price (AWP) is the average price that retailers and others are reportedly paying for a particular drug. The AWP is reported by the manufacturers and compiled by independent publishers, the data of which is used by governments, insurance companies, and others to determine the reimbursement and retail prices of prescription drugs. Because AWP relies on third-party reporting—and is, therefore, vulnerable to price manipulation—some institutions have begun to abandon its use in favor of the SWP.

Finally, the Direct Price (DIRP or DP) is the price a non-wholesale buyer (e.g. you) would expect to pay at the cash register. Generally speaking, there's a 20-30% mark-up between the WAC and DIRP.

Suggested Wholesale Price (SWP) of Brand Name Antiretrovirals Per Month

Antiretroviral Drug Adult Strength Dose Count SWP
Aptivus (tiprinavir) 250mg capsule 2 twice daily 120 $1,335.14
Atripla (tenofovir + emtricitabine + efavirenz) 300/200/600mg tablet 1 daily 30 $2,253.88
Combivir (zidovudine + lamivudine) 300/150mg tablet 1 twice daily 60 $1,081.70
Complera (tenofovir + emtricitabine + ripilvirine) 300/200/25mg tablet 1 daily 30 $2,195.83
Crixivan (indinavir) 400mg capsule 2 twice daily 120 $365.42*
Crixivan (indinavir) 400mg capsule 2 thrice daily 180 $548.12
Edurant (ripilvirine) 25mg tablet 1 daily 30 $804.38*
Emtriva (emtricitabine) 200mg capsule 1 daily 30 $574.14
Epivir (lamivudine) 300mg tablet 1 daily 30 $498.89
Epzicom (abacavir + lamivudine) 600/300mg tablet 1 daily 30 $1,118.90
Fuzeon (enfuviritide) 90mg injection 1 twice daily 60 $3,248.72
Intelence (etravirine) 200mg tablet 1 twice daily 60 $978.64
Intelence (etravirine) 200mg tablet 1 twice daily 60 $978.64
Isentress (ratelgravir) 400mg tablet 1 twice daily 60 $1,228.69
Isentress (ratelgravir) 400mg tablet 1 twice daily 60 $1,228.69
Invirase (saquinavir) 500mg tablet 2 twice daily 120 $1,088.84
Kaletra (lopinavir + ritonavir) 250/50mg tablet 2 twice daily or 4 daily 120 $871.36
Lexiva (fosamprenavir) 700mg tablet 2 twice daily 120 $1,988.96
Lexiva (fosamprenavir) 700mg tablet 1 twice daily or 2 daily 60 $994.48
Norvir (ritonavir) 100mg tablet 1 daily 30 $308.60
Norvir (ritonavir) 100mg tablet 1 twice daily 60 $617.20
Norvir (ritonavir) 100mg tablet 2 twice daily 120 $1,234.40
Prezista (darunavir) 400mg tablet 2 daily 60 $1,230.20
Prezista (darunavir) 600mg tablet 1 twice daily 60 $1,230.20
Rescriptor (delavirdine) 200mg tablet 2 thrice daily 180 $365.45*
Retrovir (zidovudine) 300mg tablet 1 twice daily 60 $557.83
Reyataz (atazanavir) 150mg capsule 2 daily 60 $1,222.10
Reyataz (atazanavir) 200mg capsule 2 daily 60 $1,222.10
Reyataz (atazanavir) 300mg capsule 1 daily 30 $1,210.56
Selzentry (maraviroc) 150mg tablet 1 twice daily 60 $1,259.82
Selzentry (maraviroc) 300mg tablet 1 twice daily 60 $1,259.82
Stribild (tenofovir + emtricitabine + elvitegravir + cobicistat) 300/200/150/ 150mg tablet 1 daily 30 $2,810.96
Sustiva (efavirenz) 600mg tablet 1 daily 30 $785.90
Tivicay (dolutegravir) 50mg tablet 1 daily 30 $1,175.00**
Trizivir (abacavir + zidovudine + lamivudine) 300/300/100mg tablet 1 twice daily 60 $785.90
Truvada (tenofovir + emtricitabine) 300/150mg tablet 1 daily 30 $1,467.97
Truvada (tenofovir + emtricitabine) 300/150mg tablet 1 daily 30 $1,467.97
Videx EC (didanosine) 400mg capsule 1 daily 30 $478.08
Viracept (nelfinavir) 625mg tablet 2 twice daily 120 $879.84*
Viramune (nevirapine) 200mg tablet 1 twice daily 60 $723.08
Viramune XR (nevirapine) 400mg tablet 1 daily 30 $670.63
Viread (tenofovir) 300mg tablet 1 daily 30 $998.80
Zerit (stavudine) 40mg capsule 1 twice daily 60 $512.62
Ziagen (abacavir) 300mg tablet 2 daily 60 $670.37

* - SWP from March 27, 2012; no SWP published in February 12, 2013 Update.
** - Wholesale Acquisition Cost (WAC) price; SWP pending following FDA approval on August 12, 2013.

Sources:

National Institutes of Health (NIH). "Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents - Appendix B: Drug Characteristics Tables (Monthly Suggested Wholesale Price of Antiretroviral Drugs)." Bethesda, Maryland; Updated February 12, 2013.

  1. About.com
  2. Health
  3. AIDS / HIV
  4. HIV/AIDS FAQs
  5. Treatment Questions
  6. The Wholesale Price of HIV Drugs

©2014 About.com. All rights reserved.

We comply with the HONcode standard
for trustworthy health
information: verify here.